Current
Neuro-Oncology


Volume 18 Number 2
29 February 2016


Home > Publications > Current Neuro-Oncology > Volume 18, Year 2016 > Number 2, 29 February






Chakraborty S, Priamo F, Boockvar JA.
Magnetic Resonance Imaging to Identify Glioblastoma Molecular Phenotypes.
Neurosurgery. 2016 Feb 1;78(2):N20-1. doi: 10.1227/01.neu.0000479895.10242.9d. PMID: 26779797 Comment. ˍ
Refers to: Itakura H, et al., Magnetic resonance image features identify glioblastoma phenotypic subtypes with distinct molecular pathway activities.
Sci Transl Med. 2015 Sep 2;7(303):303ra138. doi: 10.1126/scitranslmed.aaa7582. PMID: 26333934. Observational study. ˍ



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Redjal N, Reinshagen C, Le A, Walcott BP, McDonnell E, Dietrich J, Nahed BV.
Valproic acid, compared to other antiepileptic drugs, is associated with improved overall and progression-free survival in glioblastoma but worse outcome in grade II/III gliomas treated with temozolomide.
J Neurooncol. 2016 Feb 1, 2016;127(3):505-14
. doi: 10.1007/s11060-016-2054-8. PMID: 26830093. Observational study. ˍ




Zussman BM, Engh JA.
Patterns of Care and Clinical Decision Making for Recurrent Glioblastoma Multiforme.
Neurosurgery.
2016 Feb 1;78(2):N12-4. doi: 10.1227/01.neu.0000479889.72124.20. PMID: 26779791. Comment. ˍ
Refers to: Hundsberger T, et al., Patterns of care in recurrent glioblastoma in Switzerland: a multicentre national approach based on diagnostic nodes.
J Neurooncol. 2015 Oct 12, 2016;126(1):175-183. doi: 10.1007/s11060-015-1957-0. PMID: 26459327. Interventional study. ˍˍˍ




Romero D.
Genetics: Divergence shapes recurrence.
Nat Rev Clin Oncol. 2016 Feb 2, 2016;13(3):136. doi: 10.1038/nrclinonc.2016.14. PMID: 26831182. Comment. ˍ
Refers to: Morrissy AS, et al., Divergent clonal selection dominates medulloblastoma at recurrence.
Nature. 2016 Jan 13, 2016;529(7586):351-7. doi: 10.1038/nature16478. PMID: 26760213. Laboratory investigation. ˍ




Wheeler LA, Manzanera AG, Bell SD, Cavaliere R, McGregor JM, Grecula JC, Newton HB, Lo SS, Badie B, Portnow J, Teh BS, Trask TW, Baskin DS, New PZ, Aguilar LK, Aguilar-Cordova E, Chiocca EA.
Phase 2 multicenter study of gene-mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma.
Neuro Oncol. 2016 Feb 2, 2016;18(8):1137-45
. doi: 10.1093/neuonc/now002. PMID: 26843484. Interventional study. ˍ




Balana C, De Las Penas R, Sepúlveda JM, Gil-Gil MJ, Luque R, Gallego O, Carrato C, Sanz C, Reynes G, Herrero A, Ramirez JL, Pérez-Segura P, Berrocal A, Vieitez JM, Garcia A, Vazquez-Estevez S, Peralta S, Fernandez I, Henriquez I, Martinez-Garcia M, De la Cruz JJ, Capellades J, Giner P, Villà S.
Bevacizumab and temozolomide versus temozolomide alone as neoadjuvant treatment in unresected glioblastoma: the GENOM 009 randomized phase II trial.
J Neurooncol. 2016 Feb 3, 2016;127(3):569-79
. doi: 10.1007/s11060-016-2065-5. PMID: 26847813. Interventional study. ˍ




Jungk C, Chatziaslanidou D, Ahmadi R, Capper D, Bermejo JL, Exner J, von Deimling A, Herold-Mende C, Unterberg A.
Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients.
BMC Cancer. 2016 Feb 10;16:81
. doi: 10.1186/s12885-016-2131-6. PMID: 26865253. Observational study. ˍ




Vogelbaum MA.
The benefit of surgical resection in recurrent glioblastoma.
Neuro Oncol. 2016 Feb 10, 2016;18(4):462-3
. doi: 10.1093/neuonc/now004. PMID: 26869588. Editorial. ˍ
Refers to: Suchorska B, et al., Complete resection of contrast-enhancing tumor volume is associated with improved survival in recurrent glioblastoma-results from the DIRECTOR trial.
Neuro Oncol. 2016 Jan 27, 2015;18(4):549-56
. doi: 10.1093/neuonc/nov326. PMID: 26823503. Interventional study. ˍ




Brandes AA, Bartolotti M, Tosoni A, Poggi R, Bartolini S, Paccapelo A, Bacci A, Ghimenton C, Pession A, Bortolotti C, Zucchelli M, Galzio R, Talacchi A, Volpin L, Marucci G, de Biase D, Pizzolitto S, Danieli D, Ermani M, Franceschi E.
Patient outcomes following second surgery for recurrent glioblastoma.
Future Oncol. 2016 Feb 16;12(8):1039-44
. doi: 10.2217/fon.16.9. PMID: 26880307. Observational study. ˍ




Kruser TJ, Mehta MP, Kozak KR.
Identification of Patients Who Benefit From Bevacizumab in High-Grade Glioma-An Easy Question Turned Difficult: Treat the Scan or the Patient?
J Clin Oncol. 2016 Feb 16, 2016;34(11):1281-2
. doi: 10.1200/JCO.2015.64.7883. PMID: 26884565. Comment. ˍ
Refers to: Taphoorn MJ, et al., Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.
J Clin Oncol. 2015 May 26, 2015;33(19):2166-75
. doi: 10.1200/JCO.2014.60.3217. PMID: 26014298. Interventional study. ˍ




Vivekanandan S, Breene R, Ramanujachar R, Traunecker H, Pizer B, Gaze MN, Saran F, Thorp N, English M, Wheeler K, Michalski A, Walker DA, Saunders D, Cowie F, Cameron A, Picton S, Parashar D, Horan G, Williams MV.
Reply to Comment on: The UK Experience of a Treatment Strategy for Pediatric Metastatic Medulloblastoma Comprising Intensive Induction Chemotherapy, Hyperfractionated Accelerated Radiotherapy, and Response-Directed High-Dose Myeloablative Chemotherapy or Maintenance Chemotherapy (Milan Strategy).
Pediatr Blood Cancer. 2016 Feb 17, 2016;63(6):1125-6
. doi: 10.1002/pbc.25946. PMID: 26891280. Letter to the Editor. ˍ
Refers to: Massimino M, et al., Comment on: The UK Experience of a Treatment Strategy for Pediatric Metastatic Medulloblastoma Comprising Intensive Induction Chemotherapy, Hyperfractionated Accelerated Radiotherapy, and Response Directed High-Dose Myeloablative Chemotherapy or Maintenance Chemotherapy (Milan Strategy).
Pediatr Blood Cancer. 2016 Jan 14. 2016;63(6):1123-4. doi: 10.1002/pbc.25901. PMID: 26766787. Letter to the Editor. ˍ
In turn referring to: Vivekanandan S, et al., The UK Experience of a Treatment Strategy for Pediatric Metastatic Medulloblastoma Comprising Intensive Induction Chemotherapy, Hyperfractionated Accelerated Radiotherapy and Response Directed High Dose Myeloablative Chemotherapy or Maintenance Chemotherapy (Milan Strategy).
Pediatr Blood Cancer. 2015 Aug 14, 2015;62(12):2132-9. doi: 10.1002/pbc.25663. PMID: 26274622. Observational study. ˍ




Purow B.
For glioma, a sweet side to diabetes.
Neuro Oncol. 2016 Feb 19, 2015;18(3):306-7
. doi: 10.1093/neuonc/nov328. PMID: 26917588. Editorial. ˍ
Refers to: Seliger C, et al., Diabetes, use of antidiabetic drugs, and the risk of glioma.
Neuro Oncol. 2015 Jun 20, 2015;18(3):340-9
. doi: 10.1093/neuonc/nov100. PMID: 26093337. Observational study. ˍ




Brandes AA, Carpentier AF, Kesari S, Sepulveda-Sanchez JM, Wheeler HR, Chinot O, Cher L, Steinbach JP, Capper D, Specenier P, Rodon J, Cleverly A, Smith C, Gueorguieva I, Miles C, Guba SC, Desaiah D, Lahn MM, Wick W.
A phase II randomized study of galunisertib monotherapy or galunisertib plus lomustine compared with lomustine monotherapy in patients with recurrent glioblastoma.
Neuro Oncol. 2016 Feb 21, 2016;18(8):1146-56
. doi: 10.1093/neuonc/now009. PMID: 26902851. Interventional study. ˍ




Steffens R, Semrau S, Lahmer G, Putz F, Lettmaier S, Eyüpoglu I, Buchfelder M, Fietkau R.
Recurrent glioblastoma: who receives tumor specific treatment and how often?
J Neurooncol. 2016 Feb 23, 2016;128(1):85-92
. doi: 10.1007/s11060-016-2079-z. PMID: 26907492. Observational study. ˍ




Cernelc J.
Glioblastoma with a PNET component - Report of an emerging variant with therapeutic and prognostic implications.
Pathology. 2016 Feb 1, 2016;48 Suppl 1:S66
. doi: 10.1016/j.pathol.2015.12.166. Case report (Meeting abstract). ˍ