Current
Neuro-Oncology


Volume 18 Number 12
31 December 2016


Home > Publications > Current Neuro-Oncology > Volume 18, Year 2016 > Number 12, 31 December






Strebe JK, Lubin JA, Kuo JS.
"Tag Team" Glioblastoma Therapy: Results From a Phase 1 Trial of Toca 511 and 5-Fluorocytosine for Recurrent High-Grade Glioma.
Neurosurgery. 2016 Dec;79(6):N18-N20
. doi: 10.1227/01.neu.0000508605.38694.fd. PMID: 27861411. Comment. ˍ
Refers to: Cloughesy TF, et al., Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma.
Sci Transl Med. 2016 Jun 1;8(341):341ra75
. doi: 10.1126/scitranslmed.aad9784. PMID: 27252174. Interventional study. ˍ




Cloughesy T, Finocchiaro G, Belda-Iniesta C, Recht L, Brandes AA, Pineda E, Mikkelsen T, Chinot OL, Balana C, Macdonald DR, Westphal M, Hopkins K, Weller M, Bais C, Sandmann T, Bruey JM, Koeppen H, Liu B, Verret W, Phan SC, Shames DS.
Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase II Study of Onartuzumab Plus Bevacizumab Versus Placebo Plus
Bevacizumab in Patients With Recurrent Glioblastoma: Efficacy, Safety, and Hepatocyte Growth Factor and O6-Methylguanine-DNA Methyltransferase Biomarker Analyses.
J Clin Oncol. 2016 Dec 5, 2017;35(3):343-351. doi: 10.1200/JCO.2015.64.7685. PMID: 27918718. Interventional study. ˍ




O'Connell D, Shen V, Loudon W, Bota DA.
First report of tumor treating fields use in combination with bevacizumab in a pediatric patient: a Case report.
CNS Oncol. 2016 Dec 5, 2017;6(1):11-18. doi: 10.2217/cns-2016-0018. PMID: 27918194. Case report. ˍ




Yoo RE, Choi SH, Kim TM, Park CK, Park SH, Won JK, Kim IH, Lee ST, Choi HJ, You SH, Kang KM, Yun TJ, Kim JH, Sohn CH.
Dynamic contrast-enhanced MR imaging in predicting progression of enhancing lesions persisting after standard treatment in glioblastoma patients: a prospective study.
Eur Radiol. 2016 Dec 14, 2017;27(8):3156-3166. doi: 10.1007/s00330-016-4692-9. PMID: 27975145. Interventional study. ˍ




Portnow J, Synold TW, Badie B, Tirughana R, Lacey SF, D'Apuzzo M, Metz MZ, Najbauer J, Bedell V, Vo T, Gutova M, Frankel P, Chen MY, Aboody KS.
Neural stem cell-based anti-cancer gene therapy: a first-in-human study in recurrent high grade glioma patients.
Clin Cancer Res. 2016 Dec 15, 2017;23(12):2951-2960. doi: 10.1158/1078-0432.CCR-16-1518. PMID: 27979915. Interventional study. ˍ




Winkler F.
Tumour network in glioma.
ESMO Open. 2016 Dec 19, 2016;1(6):e000133. doi: 10.1136/esmoopen-2016-000133. PMID: 28255455. Podcast. ˍ




Esbenshade AJ, Kocak M, Hershon L, Rousseau P, Decarie JC, Shaw S, Burger P, Friedman HS, Gajjar A, Moghrabi A.
A Phase II feasibility study of oral etoposide given concurrently with radiotherapy followed by dose intensive adjuvant chemotherapy for children with newly diagnosed high-risk medulloblastoma (protocol POG 9631): A report from the Children's Oncology Group.
Pediatr Blood Cancer. 2016 Dec 21, 2017;64(6):10.1002/pbc.26373. doi: 10.1002/pbc.26373. PMID: 28000417. Interventional study. ˍ




Weller M, Holland EC, Hambardzumyan D.
Reply: Corticosteroids compromise survival in glioblastoma in part through their elevation of blood glucose levels.
Brain. 2016 Dec 21, 2017;140(3):e17. doi: 10.1093/brain/aww325. PMID: 28007996. Comment. ˍ
Refers to: Klement RJ, et al., Corticosteroids compromise survival in glioblastoma in part through their elevation of blood glucose levels.
Brain. 2016 Dec 30, 2017;140(3):e16. doi: 10.1093/brain/aww324. PMID: 28007995. Letter to the Editor. ˍ
In turn referring to: Pitter KL, et al., Corticosteroids compromise survival in glioblastoma.
Brain. 2016 Mar 28, 2016;139(Pt 5):1458-71
. doi: 10.1093/brain/aww046. PMID: 27020328. Observational study. ˍ




Miller C, Guillaume D, Dusenbery K, Clark HB, Moertel C.
Report of effective trametinib therapy in 2 children with progressive hypothalamic optic pathway pilocytic astrocytoma: documentation of volumetric response.
J Neurosurg Pediatr. 2016 Dec 23, 2017;19(3):319-324. doi: 10.3171/2016.9.PEDS16328. PMID: 28009226. Case report. ˍ




Peddi P, Ajit NE, Burton GV, El-Osta H.
Regression of a glioblastoma multiforme: spontaneous versus a potential antineoplastic effect of dexamethasone and levetiracetam.
BMJ Case Rep. 2016 Dec 23, 2016:bcr2016217393. doi: 10.1136/bcr-2016-217393. PMID: 28011886. Case report. ˍ




Toledo M, Sarria-Estrada S, Quintana M, Maldonado X, Martinez-Ricarte F, Rodon J, Auger C, Aizpurua M, Salas-Puig J, Santamarina E, Martinez-Saez E.
Epileptic features and survival in glioblastomas presenting with seizures.
Epilepsy Res. 2016 Dec 26, 2017;130:1-6. doi: 10.1016/j.eplepsyres.2016.12.013. PMID: 28073027. Interventional study. ˍ




Zwirner K, Paulsen F, Schittenhelm J, Borchers C, Skardelly M, Zips D, Eckert F.
Prognostic parameters and outcome after re-irradiation for progressive glioblastoma.
Acta Neurol Scand. 2016 Dec 26, 2017;136(3):239-245. doi: 10.1111/ane.12719. PMID: 28025828. Observational study. ˍ




Brown CE, Alizadeh D, Starr R, Weng L, Wagner JR, Naranjo A, Ostberg JR, Blanchard MS, Kilpatrick J, Simpson J, Kurien A, Priceman SJ, Wang X, Harshbarger TL, D'Apuzzo M, Ressler JA, Jensen MC, Barish ME, Chen M, Portnow J, Forman SJ, Badie B.
Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy.
N Engl J Med. 2016 Dec 29, 2016;375(26):2561-9. doi: 10.1056/NEJMoa1610497. PMID: 28029927. Interventional study. ˍ




Reardon DA, Lassman AB, van den Bent M, Kumthekar P, Merrell R, Scott AM, Fichtel L, Sulman EP, Gomez E, Fischer J, Lee HJ, Munasinghe W, Xiong H, Mandich H, Roberts-Rapp L, Ansell P, Holen KD, Gan HK.
Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma.
Neuro Oncol. 2016 Dec 29, 2017;19(7):965-975. doi: 10.1093/neuonc/now257. PMID: 28039367. Interventional study. ˍ




Becher OJ, Gilheeney SW, Khakoo Y, Lyden DC, Haque S, De Braganca KC, Kolesar JM, Huse JT, Modak S, Wexler LH, Kramer K, Spasojevic I, Dunkel IJ.
A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors.
Pediatr Blood Cancer. 2016 Dec 30. 2017;64(7):e26409. doi: 10.1002/pbc.26409. PMID: 28035748. Interventional study. ˍ




Klement RJ, Champ CE.
Corticosteroids compromise survival in glioblastoma in part through their elevation of blood glucose levels.
Brain. 2016 Dec 30, 2017;140(3):e16. doi: 10.1093/brain/aww324. PMID: 28007995. Letter to the Editor. ˍ
Refers to: Pitter KL, et al., Corticosteroids compromise survival in glioblastoma.
Brain. 2016 Mar 28, 2016;139(5):1458-71
. doi: 10.1093/brain/aww046. PMID: 27020328. Observational study. ˍ