Current Neuro-Oncology




Volume 24 Number 7
15 April 2022




Home > Publications > Current Neuro-Oncology > Volume 24, Year 2022 > Number 7, 15 April






Eckstein OS, Allen CE, Williams PM, Roy-Chowdhuri S, Patton DR, Coffey B, Reid JM, Piao J, Saguilig L, Alonzo TA, Berg SL, Ramirez NC, Jaju A, Mhlanga J, Fox E, Hawkins DS, Mooney MM, Takebe N, Tricoli JV, Janeway KA, Seibel NL, Parsons DW.
Phase II Study of Selumetinib in Children and Young Adults With Tumors Harboring Activating Mitogen-Activated Protein Kinase Pathway Genetic Alterations: Arm E of the NCI-COG Pediatric MATCH Trial.
J Clin Oncol. 2022 Apr 1;
40(20):2235-2245. doi: 10.1200/JCO.21.02840. PMID: 35363510. Interventional study˰ ˍ




Guan Y, Li J, Gong X, Zhu H, Li C, Mei G, Liu X, Pan L, Dai J, Wang Y, Wang E, Liu Y, Wang X.
Safety and Efficacy of Hypofractionated Stereotactic Radiotherapy with Anlotinib Targeted Therapy for Glioblastoma at the First Recurrence: A Preliminary Report.
Brain Sci. 2022 Apr 2;12(4):471
. doi: 10.3390/brainsci12040471. PMID: 35448002. Observational study. ˍ




Galanis E, Anderson SK, Twohy E, Butowski NA, Hormigo A, Schiff D, Omuro A, Jaeckle KA, Kumar S, Kaufmann TJ, Geyer S, Kumthekar PU, Campian J, Giannini C, Buckner JC, Wen PY.
Phase I/randomized phase II trial of TRC105 plus bevacizumab versus bevacizumab in recurrent glioblastoma: North Central Cancer Treatment Group N1174 (Alliance).
Neurooncol Adv. 2022 Apr 4;4(1):vdac041
. doi: 10.1093/noajnl/vdac041. PMID: 35664553. Interventional study. ˍ




Narita Y, Okita Y, Arakawa Y.
Evaluation of the efficacy and safety of TAS0313 in adults with recurrent glioblastoma.
Cancer Immunol Immunother. 2022 Apr 4
. doi: 10.1007/s00262-022-03184-7. PMID: 35377001. Interventional study. ˍ




Wang X, Zhang Y, Li ZY, Bao JF.
Glioblastoma in lateral ventricle: A case report.
Asian J Surg. 2022 Apr 4;
45(8):1648-1649. doi: 10.1016/j.asjsur.2022.03.070. PMID: 35393221. Case report. ˍ




Chen B, Chen C, Zhao Y, Cui W, Xu J.
The role of chemotherapy in the treatment of adult medulloblastoma.
World Neurosurg. 2022 Apr 6;
163:e435-e449. doi: 10.1016/j.wneu.2022.04.004. PMID: 35398321. Observational study˰ ˍ




de Groot JF, Kim AH, Prabhu S, Rao G, Laxton AW, Fecci PE, O'Brien BJ, Sloan A, Chiang V, Tatter SB, Mohammadi AM, Placantonakis DG, Strowd RE, Chen C, Hadjipanayis C, Khasraw M, Sun D, Piccioni D, Sinicrope KD, Campian JL, Kurz SC, Williams B, Smith K, Tovar-Spinoza Z, Leuthardt EC.
Efficacy of laser interstitial thermal therapy (LITT) for newly diagnosed and recurrent IDH wild-type glioblastoma.
Neurooncol Adv. 2022 Apr 6;4(1):vdac040
. doi: 10.1093/noajnl/vdac040. PMID: 35611270. Observational study. ˍ




Yan Z, Zhang X, Hua L, Huang L.
Melatonin inhibits the malignant progression of glioblastoma via regulating miR-16-5p/PIM1.
Curr Neurovasc Res. 2022 Apr 6
. doi: 10.2174/1567202619666220406084947. PMID: 35388757. Laboratory investigation˰ ˍ




Desai AV, Robinson GW, Gauvain K, Basu EM, Macy ME, Maese L, Whipple NS, Sabnis AJ, Foster JH, Shusterman S, Yoon J, Weiss BD, Abdelbaki MS, Armstrong AE, Cash T, Pratilas CA, Corradini N, Marshall LV, Farid-Kapadia M, Chohan S, Devlin C, Meneses-Lorente G, Cardenas A, Hutchinson KE, Bergthold G, Caron H, Chow Maneval E, Gajjar A, Fox E.
Entrectinib in children and young adults with solid or primary CNS tumors harboring NTRK, ROS1 or ALK aberrations (STARTRK-NG).
Neuro Oncol. 2022 Apr 8;
24(10):1776-1789. doi: 10.1093/neuonc/noac087. PMID: 35395680. Interventional study. ˍ




Han MH, Kim JM, Cheong JH, Ryu JI, Won YD, Nam GH, Kim CH.
Efficacy of Cytokine-Induced Killer Cell Immunotherapy for Patients With Pathologically Pure Glioblastoma.
Front Oncol. 2022 Apr 8;12:851628
. doi: 10.3389/fonc.2022.851628. PMID: 35463313. Observational study. ˍ




Nayak L, Standifer N, Dietrich J, Clarke JL, Dunn GP, Lim M, Cloughesy T, Gan HK, Flagg E, George E, Gaffey S, Hayden J, Holcroft C, Wen PY, Macri M, Park AJ, Ricciardi T, Ryan A, Schwarzenberger P, Venhaus R, de Los Reyes M, Durham NM, Creasy T, Huang RY, Kaley T, Reardon DA.
Circulating Immune Cell and Outcome Analysis from the Phase 2 Study of PD-L1 Blockade with Durvalumab for Newly Diagnosed and Recurrent Glioblastoma.
Clin Cancer Res. 2022 Apr 8;
28(12):2567-2578. doi: 10.1158/1078-0432.CCR-21-4064. PMID: 35395080. Interventional study˰ ˍ




Wang Y, Pan C, Xie M, Zuo P, Li X, Gu G, Li T, Jiang Z, Wu Z, Zhang J, Zhang L.
Adult diffuse intrinsic pontine glioma: clinical, radiological, pathological, molecular features, and treatments of 96 patients.
J Neurosurg. 2022 Apr 8, 2022:1-11
. doi: 10.3171/2022.2.JNS211920. PMID: 35395636. Observational study˰ ˍ




Zhang L, Wang C, Zeng X.
Risk Factors for Early Hydrocephalus on Post Unilateral Thalamic Tumor Resection.
Front Surg. 2022 Apr 8;9:814308
. doi: 10.3389/fsurg.2022.814308. PMID: 35465419. Observational study. ˍ




Rosenberg T, Yeo KK, Mauguen A, Alexandrescu S, Prabhu SP, Tsai JW, Malinowski S, Joshirao M, Parikh K, Farouk Sait S, Rosenblum MK, Benhamida JK, Michaiel G, Tran HN, Dahiya S, Kachurak K, Friedman GK, Krystal JI, Huang MA, Margol AS, Wright KD, Aguilera D, MacDonald TJ, Chi SN, Karajannis MA.
Upfront Molecular Targeted Therapy for the Treatment of BRAF-Mutant Pediatric High-Grade Glioma.
Neuro Oncol. 2022 Apr 9;
24(11):1964-1975. doi: 10.1093/neuonc/noac096. PMID: 35397478. Observational study˰ ˍ




Chen YW, Lee YY, Lin CF, Huang TY, Ke SH, Mu PF, Pan PS, Chen JK, Lan TL, Hsu PC, Liang ML, Chen HH, Chang FC, Wu CC, Lin SC, Lee JC, Chen SK, Liu HM, Peir JJ, Tsai HY, Lin KH, Peng NJ, Chen KH, Wu YH, Kang YM, Yang WC, Liou SC, Huang WH, Tanaka H, Wong TT, Chao Y, Chou FI.
Compassionate Treatment of Brainstem Tumors with Boron Neutron Capture Therapy: A Case Series.
Life (Basel). 2022 Apr 10;12(4):566
. doi: 10.3390/life12040566. PMID: 35455057. Case report. ˍ




Choi HR, Song IA, Oh TK.
Association between surgical volume and outcomes after craniotomy for brain tumor removal: A South Korean nationwide cohort study.
J Clin Neurosci. 2022 Apr 12;100:75-81
. doi: 10.1016/j.jocn.2022.04.007. PMID: 35427988. Observational study˰ ˍ




Rodriguez D, Calmon R, Aliaga ES, Warren D, Warmuth-Metz M, Jones C, Mackay A, Varlet P, Le Deley MC, Hargrave D, Cañete A, Massimino M, Azizi AA, Saran F, Zahlmann G, Garcia J, Vassal G, Grill J, Peet A, Dineen RA, Morgan PS, Jaspan T.
MRI and Molecular Characterization of Pediatric High-Grade Midline Thalamic Gliomas: The HERBY Phase II Trial.
Radiology. 2022 Apr 12;
304(1):174-182. doi: 10.1148/radiol.211464. PMID: 35412366. Interventional study˰ ˍ



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Wang C, Liu C, Chen J, Jiang H, Zhang W, Yang L, Li X, Li Z, Peng L, Hu X, Sun P.
Effect of neoadjuvant iodine-125 brachytherapy upon resection of glioma.
BMC Cancer. 2022 Apr 12;22(1):397
. doi: 10.1186/s12885-022-09504-5. PMID: 35413858. Observational study. ˍ




Grogan PT, Deming DA, Helgager J, Ruszkiewicz T, Baskaya MK, Howard SP, Robins HI.
Entrectinib demonstrates prolonged efficacy in an adult case of radiation-refractory NTRK fusion glioblastoma.
Neurooncol Adv. 2022 Apr 13;4(1):vdac046
. doi: 10.1093/noajnl/vdac046. PMID: 35673607. Case report. ˍ



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Han S, Qu FW, Wang PF, Liu YX, Li SW, Yan CX.
Development and Validation of a Nomogram Model Based on Hematological Indicators for Predicting the Prognosis of Diffused Gliomas.
Front Surg. 2022 Apr 13;9:803237
. doi: 10.3389/fsurg.2022.803237. PMID: 35495765. Observational study. ˍ




Pantalone MR, Rahbar A, Söderberg-Naucler C, Stragliotto G.
Valganciclovir as Add-on to Second-Line Therapy in Patients with Recurrent Glioblastoma.
Cancers (Basel). 2022 Apr 13;14(8):1958
. doi: 10.3390/cancers14081958. PMID: 35454863. Observational study. ˍ




Sridhar S, Paul MR, Yeh-Nayre L, Khanna PC, Elster J, Aristizabal P, Crawford JR.
Single-agent Bevacizumab in the Treatment of Symptomatic Newly Diagnosed and Recurrent/Refractory Pediatric Cervicomedullary Brainstem Low-grade Gliomas: A Single Institutional Experience.
J Pediatr Hematol Oncol. 2022 Apr 13
. doi: 10.1097/MPH.0000000000002462. PMID: 35426868. Observational study˰ ˍ




Wang X, Yu X, Xu H, Wei K, Wang S, Wang Y, Han J.
Serum-derived extracellular vesicles facilitate temozolomide resistance in glioblastoma through a HOTAIR-dependent mechanism.
Cell Death Dis. 2022 Apr 13;13(4):344
. doi: 10.1038/s41419-022-04699-8. PMID: 35418162. Laboratory investigation. ˍ




Zheng L, Gong J, Yu T, Zou Y, Zhang M, Nie L, Chen X, Yue Q, Liu Y, Mao Q, Zhou Q, Chen N.
Diffuse Midline Gliomas With Histone H3 K27M Mutation in Adults and Children: A Retrospective Series of 164 Cases.
Am J Surg Pathol. 2022 Apr 13
. doi: 10.1097/PAS.0000000000001897. PMID: 35416795. Observational study. ˍ




Omuro A, Brandes AA, Carpentier AF, Idbaih A, Reardon DA, Cloughesy T, Sumrall A, Baehring J, van den Bent M, Bähr O, Lombardi G, Mulholland P, Tabatabai G, Lassen U, Sepulveda JM, Khasraw M, Vauleon E, Muragaki Y, Di Giacomo AM, Butowski N, Roth P, Qian X, Fu AZ, Liu Y, Potter V, Chalamandaris AG, Tatsuoka K, Lim M, Weller M.
Radiotherapy Combined With Nivolumab or Temozolomide for Newly Diagnosed Glioblastoma With Unmethylated MGMT Promoter: An International Randomized Phase 3 Trial.
Neuro Oncol. 2022 Apr 14, 2022:noac099
. doi: 10.1093/neuonc/noac099. PMID: 35419607. Interventional study. ˍ



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Lee J, Grabowski MM, Lathia JD.
Tumor Treating Fields: killing two birds with one stone.
J Clin Invest. 2022 Apr 15;132(8):e159073
. doi: 10.1172/JCI159073. PMID: 35426370. Comment. ˍ
Refers to: Chen D, et al.,Tumor Treating Fields dually activate STING and AIM2 inflammasomes to induce adjuvant immunity in glioblastoma.
J Clin Invest. 2022 Feb 24;132(8):e149258
. doi: 10.1172/JCI149258. PMID: 35199647. Laboratory investigation. ˍ