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Astrocytoma | Etiopathogenesis | IDH mutant

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Shi ZF, Li KK, Kwan JS, Chung NY, Wong SC, Chu AW, Chen H, Chan DT, Mao Y, Ng HK.
The molecular history of IDH-mutant astrocytomas without adjuvant treatment.
Brain Pathol. 2024 Oct 30:e13300. doi: 10.1111/bpa.13300. PMID: 39473241. Observational study. ˍ

Hinz F, Friedel D, Korshunov A, Ippen FM, Bogumil H, Banan R, Brandner S, Hasselblatt M, Boldt HB, Dirse V, Dohmen H, Aronica E, Brodhun M, Broekman MLD, Capper D, Cherkezov A, Deng MY, van Dis V, Felsberg J, Frank S, French PJ, Gerlach R, Göbel K, Goold E, Hench J, Kantelhardt S, Kohlhof-Meinecke P, Krieg S, Mawrin C, Morrison G, Mühlebner A, Ozduman K, Pfister SM, Poliani PL, Prinz M, Reifenberger G, Riemenschneider MJ, Sankowski R, Schrimpf D, Sill M, Snuderl M, Verdijk RM, Voisin MR, Wesseling P, Wick W, Reuss DE, von Deimling A, Sahm F, Maas SLN, Suwala AK.
IDH-mutant astrocytomas with primitive neuronal component have a distinct methylation profile and a higher risk of leptomeningeal spread.
Acta Neuropathol. 2025 Feb 3;149(1):12. doi: 10.1007/s00401-025-02849-8. PMID: 39899075. Observational study. ˍ