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Glioblastoma | Treatment | Microenvironment modulators
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Vogiatzi I, Lama LM, Lehmann A, Rossignoli F, Gettemans J, Shah K.
Allogeneic stem cells engineered to
release interferon β and scFv-PD1 target glioblastoma and
alter the tumor microenvironment.
Cytotherapy.
2024 May 17:S1465-3249(24)00719-9. doi:
10.1016/j.jcyt.2024.05.012. PMID:
38852095. Laboratory investigation. ˍ
Chen
JJ, Vincent MY, Shepard D, Peereboom D, Mahalingam D, Battiste J,
Patel MR, Juric D, Wen PY, Bullock A, Selfridge JE, Pant S, Liu J,
Li W, Fyfe S, Wang S, Zota V, Mahoney J, Watnick RS, Cieslewicz M,
Watnick J.
Phase
1 dose expansion and biomarker study assessing first-in-class
tumor microenvironment modulator VT1021 in patients with advanced
solid tumors.
Commun
Med (Lond).
2024 May 21;4(1):95. doi:
10.1038/s43856-024-00520-z. PMID:
38773224. Interventional study. ˍ