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Gliomas | Treatment | Pharmacotherapy | Anti-hyperglycemic

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Qiao X, Wang Z, Chen Y, Peng N, Zhang H, Niu C, Cheng C.
Combined metformin and simvastatin therapy inhibits SREBP2 maturation and alters energy metabolism in glioma.
Cell Death Dis. 2024 Nov 9;15(11):809. doi: 10.1038/s41419-024-07169-5. PMID: 39521788. Laboratory investigation. ˍ

Basheer HA, Salman NM, Abdullah RM, Elsalem L, Afarinkia K.
Metformin and glioma: Targeting metabolic dysregulation for enhanced therapeutic outcomes.
Transl Oncol. 2025 Feb 18;53:102323. doi: 10.1016/j.tranon.2025.102323. PMID: 39970627. Review. ˍ