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High-grade gliomas | Treatment | Targeted therapy | Trametinib
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Kawaguchi
Y, Watanabe Y, Miyakita Y, Ohno M, Ogawa C, Takahashi M,
Yanagisawa S, Mukai T, Igaki H, Sugino H, Yoshida A, Narita Y.
Successful treatment of pediatric
patients with high-grade gliomas featuring leptomeningeal
metastases by targeting BRAF V600E mutations with dabrafenib plus
trametinib: two illustrative cases.
Int
Cancer Conf J. 2024 Apr 10;13(3):256-262. doi:
10.1007/s13691-024-00674-6. PMID:
38962052. Case report˰
ˍ
Castelli B, Tellini M, Guidi M, Di Nicola M, Giunti L, Buccoliero
AM, Censullo ML, Iacono A, Desideri I, Genitori L, Sardi I, Fonte
C.
Case report: complete long-lasting
response to multimodal third line treatment with neurosurgical
resection, carmustine wafer implantation and dabrafenib plus
trametinib in a BRAFV600E
mutated high-grade glioma.
Front
Oncol. 2024 May 7;14:1359093. doi:
10.3389/fonc.2024.1359093. PMID:
38774414. Case report. ˍ