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Pediatric CNS tumors | Treatment | Immunotherapy | CAR-T-cells






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Lin FY, Stuckert A, Tat C, White M, Ruggieri L, Zhang H, Mehta B, Lapteva N, Mei Z, Major A, Thakkar S, Shum T, Parikh K, Wu MF, Lindsay HB, Scherer L, Shekar M, Baxter P, Wang T, Grilley B, Moeller K, Hicks J, Roy A, Anastas J, Malbari F, Aldave G, Chintagumpala M, Blaney S, Parsons DW, Brenner MK, Heslop HE, Rooney CM, Omer B.
Phase I Trial of GD2.CART Cells Augmented With Constitutive Interleukin-7 Receptor for Treatment of High-Grade Pediatric CNS Tumors.
J Clin Oncol. 2024 May 21:JCO2302019. doi: 10.1200/JCO.23.02019. PMID: 38771986. Interventional study. ˍ




Ronsley R, Bertrand KC, Song EZ, Timpanaro A, Choe M, Tlais D, Vitanza NA, Park JR.
CAR T cell therapy for pediatric central nervous system tumors: a review of the literature and current North American trials.
Cancer Metastasis Rev. 2024 Sep 9. doi: 10.1007/s10555-024-10208-4. PMID: 39251462. Review. ˍ