Current Neuro-Oncology




Volume 23 Number 19
15 October 2021




Home > Publications > Current Neuro-Oncology > Volume 23, Year 2021 > Number 19, 15 October






Carnevale JA, Babu CS, Goldberg JL, Fong R, Schwartz TH.
Visual deterioration after endonasal endoscopic skull base surgery: causes, treatments, and outcomes.
J Neurosurg. 2021 Oct 1, 2021:1-11
. doi: 10.3171/2021.3.JNS204378. PMID: 34598134. Observational study. ˍ




Ort J, Hamou HA, Kernbach JM, Hakvoort K, Blume C, Lohmann P, Galldiks N, Heiland DH, Mottaghy FM, Clusmann H, Neuloh G, Langen KJ, Delev D.
18F-FET-PET-guided gross total resection improves overall survival in patients with WHO grade III/IV glioma: moving towards a multimodal imaging-guided resection.
J Neurooncol. 2021 Oct 1
. doi: 10.1007/s11060-021-03844-1. PMID: 34599479. Observational study. ˍ



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Tsai HC, Wei KC, Chen PY, Huang CY, Chen KT, Lin YJ, Cheng HW, Chen YR, Wang HT.
Valproic Acid Enhanced Temozolomide-Induced Anticancer Activity in Human Glioma Through the p53-PUMA Apoptosis Pathway.
Front Oncol. 2021 Oct 1, 2021;11:722754
. doi: 10.3389/fonc.2021.722754. PMID: 34660288. Observational study. ˍ




Bota DA, Mason W, Kesari S, Magge R, Winograd B, Elias I, Reich SD, Levin N, Trikha M, Desjardins A.
Marizomib alone or in combination with bevacizumab in patients with recurrent glioblastoma: Phase I/II clinical trial data.
Neurooncol Adv. 2021 Oct 2, 2021;3(1):vdab142
. doi: 10.1093/noajnl/vdab142. PMID: 34729484. Interventional study. ˍ




Wang Z, Du F, Ren Y, Jiang W.
Treatment of MGMT promoter unmethylated glioblastoma with PD-1 inhibitor combined with anti-angiogenesis and epidermal growth factor receptor tyrosine kinase inhibitor: a case report.
Ann Transl Med. 2021 Oct 2, 2021;9(19):1508
. doi: 10.21037/atm-21-4625. PMID: 34805370. Case report. ˍ




Fiondella L, Cavallieri F, Napoli M, Froio E, Serra S, Borsari S, Giaccherini L, Ghadirpour R, Cozzi S, Pascarella R, Longo C, Valzania F, Pisanello A.
Glioblastoma and malignant melanoma: Serendipitous or anticipated association?
Neuropathology. 2021 Oct 3
. doi: 10.1111/neup.12771. PMID: 34605073. Letter to Editor˰ ˍ




Patel NV, Wong T, Fralin SR, Li M, McKeown A, Gruber D, D'Amico RS, Patsalides A, Tsiouris A, Stefanov DG, Flores O, Zlochower A, Filippi CG, Ortiz R, Langer DJ, Boockvar JA.
Repeated superselective intraarterial bevacizumab after blood brain barrier disruption for newly diagnosed glioblastoma: a phase I/II clinical trial.
J Neurooncol. 2021 Oct 3
. doi: 10.1007/s11060-021-03851-2. PMID: 34601657. Interventional study˰ ˍ




Celli M, Caroli P, Amadori E, Arpa D, Gurrieri L, Ghigi G, Cenni P, Paganelli G, Matteucci F.
Diagnostic and Prognostic Potential of 18F-FET PET in the Differential Diagnosis of Glioma Recurrence and Treatment-Induced Changes After Chemoradiation Therapy.
Front Oncol. 2021 Oct 4, 2021;11:721821
. doi: 10.3389/fonc.2021.721821. PMID: 34671551. Observational study. ˍ




Lovo EE, Moreira A, Barahona KC, Ramirez J, Campos F, Tobar C, Caceros V, Sallabanda M, Sallabanda K.
Stereotactic Radiosurgery for Recurrent Glioblastoma Multiforme: A Retrospective Multi-Institutional Experience.
Cureus. 2021 Oct 4, 2021;13(10):e18480
. doi: 10.7759/cureus.18480. PMID: 34754642. Observational study. ˍ




Grønbæk JK, Wibroe M, Toescu S, Frič R, Thomsen BL, Møller LN, Grillner P, Gustavsson B, Mallucci C, Aquilina K, Fellows GA, Molinari E, Hjort MA, Westerholm-Ormio M, Kiudeliene R, Mudra K, Hauser P, van Baarsen K, Hoving E, Zipfel J, Nysom K, Schmiegelow K, Sehested A, Juhler M, Mathiasen R; CMS study group.
Postoperative speech impairment and surgical approach to posterior fossa tumours in children: a prospective European multicentre cohort study.
Lancet Child Adolesc Health. 2021 Oct 5, 2021;5(11):814-824
. doi: 10.1016/S2352-4642(21)00274-1. PMID: 34624241. Interventional study˰ ˍ




Narita Y, Muragaki Y, Kagawa N, Asai K, Nagane M, Matsuda M, Ueki K, Kuroda J, Date I, Kobayashi H, Kumabe T, Beppu T, Kanamori M, Kasai S, Nishimura Y, Xiong H, Ocampo C, Yamada M, Mishima K.
Safety and Efficacy of Depatuxizumab Mafodotin in Japanese Patients With Malignant Glioma: A Non-randomized, Phase 1/2 Trial.
Cancer Sci. 2021 Oct 5
. doi: 10.1111/cas.15153. PMID: 34609773. Interventional study. ˍ




Mallereau CH, Baloglu S, Chibbaro S, Noblet V, Todeschi J, Noel G, Gangi A, De Mathelin M, Proust F, Cebula H.
Does interventional MRI-guided brain cryotherapy cause a blood-brain barrier disruption? Radiological analysis and perspectives.
Neurosurg Rev. 2021 Oct 6
. doi: 10.1007/s10143-021-01637-8. PMID: 34613525. Observational study˰ ˍ




Mapelli R, Julita C, Bianchi SP, Gallina N, Lucchini R, Midulla M, Puci F, Saddi J, Trivellato S, Panizza D, De Ponti E, Arcangeli S.
Association between treatment-related lymphopenia and survival in glioblastoma patients following postoperative chemoradiotherapy.
Strahlenther Onkol. 2021 Oct 6
. doi: 10.1007/s00066-021-01855-5. PMID: 34617129. Observational study. ˍ




Maas SLN, Stichel D, Hielscher T, Sievers P, Berghoff AS, Schrimpf D, Sill M, Euskirchen P, Blume C, Patel A, Dogan H, Reuss D, Dohmen H, Stein M, Reinhardt A, Suwala AK, Wefers AK, Baumgarten P, Ricklefs F, Rushing EJ, Bewerunge-Hudler M, Ketter R, Schittenhelm J, Jaunmuktane Z, Leu S, Greenway FEA, Bridges LR, Jones T, Grady C, Serrano J, Golfinos J, Sen C, Mawrin C, Jungk C, Hänggi D, Westphal M, Lamszus K, Etminan N, Jungwirth G, Herold-Mende C, Unterberg A, Harter PN, Wirsching HG, Neidert MC, Ratliff M, Platten M, Snuderl M, Aldape KD, Brandner S, Hench J, Frank S, Pfister SM, Jones DTW, Reifenberger G, Acker T, Wick W, Weller M, Preusser M, von Deimling A, Sahm F; German Consortium on Aggressive Meningiomas (KAM).
Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Observational study, Retrospectively and Prospectively Validated.
J Clin Oncol. 2021 Oct 7, 2021:JCO2100784
. doi: 10.1200/JCO.21.00784. PMID: 34618539. Observational study. ˍ




Fusco MJ, Piña Y, Macaulay RJ, Sahebjam S, Forsyth PA, Peguero E, Walko CM.
Durable Progression-Free Survival With the Use of BRAF and MEK Inhibitors in Four Cases With BRAF V600E-Mutated Gliomas.
Cancer Control. 2021 Oct 8, 2021;28:10732748211040013
. doi: 10.1177/10732748211040013. PMID: 34620004. Case report. ˍ




Karschnia P, Weller J, Blobner J, Stoecklein VM, Dorostkar MM, Rejeski K, Forbrig R, Niyazi M, von Baumgarten L, Dietrich J, Tonn JC, Thon N.
Subventricular zone involvement is associated with worse outcome in glioma WHO grade 2 depending on molecular markers.
Sci Rep. 2021 Oct 8, 2021, 2021;11(1):20045
. doi: 10.1038/s41598-021-97714-5. PMID: 34625590. Observational study. ˍ




Momin AA, Soni P, Shao J, Nowacki AS, Suh JH, Murphy ES, Chao ST, Angelov L, Mohammadi AM, Barnett GH, Recinos PF, Kshettry VR.
Adjuvant radiation versus observation with salvage radiation after gross-total resection of WHO grade II meningiomas: a propensity score-adjusted analysis.
J Neurosurg. 2021 Oct 8, 2021:1-8
. doi: 10.3171/2021.4.JNS21559. PMID: 34624866. Observational study. ˍ




Schupper AJ, Baron RB, Cheung W, Rodriguez J, Kalkanis SN, Chohan MO, Andersen BJ, Chamoun R, Nahed BV, Zacharia BE, Kennedy J, Moulding HD, Zucker L, Chicoine MR, Olson JJ, Jensen RL, Sherman JH, Zhang X, Price G, Fowkes M, Germano IM, Carter BS, Hadjipanayis CG, Yong RL.
5-Aminolevulinic acid for enhanced surgical visualization of high-grade gliomas: a prospective, multicenter study.
J Neurosurg. 2021 Oct 8, 2021:1-10
. doi: 10.3171/2021.5.JNS21310. PMID: 34624862. Interventional study. ˍ




Cepeda S, Pérez-Nuñez A, García-García S, García-Pérez D, Arrese I, Jiménez-Roldán L, García-Galindo M, González P, Velasco-Casares M, Zamora T, Sarabia R.
Predicting Short-Term Survival after Gross Total or Near Total Resection in Glioblastomas by Machine Learning-Based Radiomic Analysis of Preoperative MRI.
Cancers (Basel). 2021 Oct 9, 2021;13(20):5047
. doi: 10.3390/cancers13205047. PMID: 34680199. Observational study. ˍ




Krivoshapkin A, Gaytan A, Abdullaev O, Salim N, Sergeev G, Marmazeev I, Cesnulis E, Killeen T, Tyuryn V, Kiselev R, Syomin P, Spallone A.
Prospective comparative study of intraoperative balloon electronic brachytherapy versus resection with multidisciplinary adjuvant therapy for recurrent glioblastoma.
Surg Neurol Int. 2021 Oct 11, 2021;12:517
. doi: 10.25259/SNI_494_2021. PMID: 34754567. Interventional study. ˍ
Erratum in: Surg Neurol Int. 2021 Dec 10, 2021;12:607. doi: 10.25259/SNI_494_2021_ER. PMID: 34992924. Correction. ˍ




Trybula SJ, Youngblood MW, Kemeny HR, Clark JR, Karras CL, Hartsell WF, Tomita T.
Radiation Induced Cavernomas in the Treatment of Pediatric Medulloblastoma: Comparative Study Between Proton and Photon Radiation Therapy.
Front Oncol. 2021 Oct 11, 2021;11:760691
. doi: 10.3389/fonc.2021.760691. PMID: 34707999. Observational study. ˍ



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Yu J, Sheng Z, Wu S, Gao Y, Yan Z, Bu C, Gu J, Bu Y, Deng K, Xu S, Chen Z, Zhang Q, Zemmar A, Hernesniemi J, Wang M, Liu G, Li T, Bu X.
Tumor DNA From Tumor In Situ Fluid Reveals Mutation Landscape of Minimal Residual Disease After Glioma Surgery and Risk of Early Recurrence.
Front Oncol. 2021 Oct 11, 2021;11:742037
. doi: 10.3389/fonc.2021.742037. PMID: 34712610. Observational study. ˍ




Bai Y, Liu T, Chen L, Gao H, Wei W, Zhang G, Wang L, Kong L, Liu S, Liu H, Roberts N, Wang M.
Study of Diffusion Weighted Imaging Derived Diffusion Parameters as Biomarkers for the Microenvironment in Gliomas.
Front Oncol. 2021 Oct 12, 2021;11:672265
. doi: 10.3389/fonc.2021.672265. PMID: 34712604. Observational study. ˍ




Ita MI, Wang JH, Toulouse A, Lim C, Fanning N, O'Sullivan M, Nolan Y, Kaar GF, Redmond HP.
The utility of plasma circulating cell-free messenger RNA as a biomarker of glioma: a pilot study.
Acta Neurochir (Wien). 2021 Oct 13
. doi: 10.1007/s00701-021-05014-8. PMID: 34643804. Interventional study. ˍ




Lu VM, Eichberg DG, Luther EM, Shah AH, Daniels DJ, Maher OM, Niazi TN.
Distinct survival and clinical profile of infantile glioblastoma: insights from a national database.
Childs Nerv Syst. 2021 Oct 13
. doi: 10.1007/s00381-021-05386-3. PMID: 34643775. Observational study˰ ˍ




Ning L, Liang W, Guo H, Liu J, Xie L.
Correlations between Clinical Characteristics and Prognosis in Patients with Grade II Glioma.
Evid Based Complement Alternat Med. 2021 Oct 13, 2021;2021:5873213
. doi: 10.1155/2021/5873213. PMID: 34712344. Observational study. ˍ




Kumar A, ArunRaj ST, Bhullar K, Haresh KP, Gupta S, Ballal S, Yadav M, Singh M, Damle NA, Garg A, Tripathi M, Bal C.
Ga-68 PSMA PET/CT in recurrent high-grade gliomas: evaluating PSMA expression in vivo.
Neuroradiology. 2021 Oct 14
. doi: 10.1007/s00234-021-02828-2. PMID: 34648046. Interventional study˰ ˍ




Arakawa Y, Sasaki K, Mineharu Y, Uto M, Mizowaki T, Mizusawa J, Sekino Y, Ono T, Aoyama H, Satomi K, Ichimura K, Kinoshita M, Ohno M, Ito Y, Nishikawa R, Fukuda H, Nishimura Y, Narita Y; Brain Tumor Study Group and Radiation Therapy Study Group of the Japan Clinical Oncology Group.
A randomized phase III study of short-course radiotherapy combined with Temozolomide in elderly patients with newly diagnosed glioblastoma; Japan clinical oncology group study JCOG1910 (AgedGlio-PIII).
BMC Cancer. 2021 Oct 15, 2021;21(1):1105
. doi: 10.1186/s12885-021-08834-0. PMID: 34654402. Interventional study Protocol. ˍ




Cluceru J, Interian Y, Phillips JJ, Molinaro AM, Luks TL, Alcaide-Leon P, Olson MP, Nair D, LaFontaine M, Shai A, Chunduru P, Pedoia V, Villanueva-Meyer JE, Chang SM, Lupo JM.
Improving the noninvasive classification of glioma genetic subtype with deep learning and diffusion-weighted imaging.
Neuro Oncol. 2021 Oct 15, 2021:noab238
. doi: 10.1093/neuonc/noab238. PMID: 34653254. Observational study. ˍ



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Liu S, Liu X, Zhuang W.
Prognostic Factors Associated With Survival in Patients With Diffuse Astrocytoma.
Front Surg. 2021 Oct 15, 2021;8:712350
. doi: 10.3389/fsurg.2021.712350. PMID: 34722621. Observational study. ˍ




Rudà R, Bruno F, Ius T, Silvani A, Minniti G, Pace A, Lombardi G, Bertero L, Pizzolitto S, Pollo B, Conti Nibali M, Pellerino A, Migliore E, Skrap M, Bello L, Soffietti R.
IDH wild-type grade 2 diffuse astrocytomas: prognostic factors and impact of treatments within molecular subgroups.
Neuro Oncol. 2021 Oct 15, 2021:noab239
. doi: 10.1093/neuonc/noab239. PMID: 34651653. Observational study. ˍ




Song AJ, Ding K, Alnahhas I, Laperriere NJ, Perry J, Mason WP, Winch C, O'Callaghan CJ, Menten JJ, Brandes AA, Phillips C, Fay MF, Nishikawa R, Osoba D, Cairncross JG, Roa W, Wick W, Shi W.
Impact of lymphopenia on survival for elderly patients with glioblastoma: A secondary analysis of the CCTG CE.6 (EORTC 26062-22061, TROG03.01) randomized clinical trial.
Neurooncol Adv. 2021 Oct 15, 2021;3(1):vdab153
. doi: 10.1093/noajnl/vdab153. PMID: 34765975. Observational study. ˍ
Erratum in: Neurooncol Adv. 2022 Jan 27;4(1):vdac011. doi: 10.1093/noajnl/vdac011. PMID: 35098127. Correction. ˍ




Yerrabothala S, Gourley BL, Ford JC, Ahmed SR, Guerin SJ, Porter M, Wishart HA, Ernstoff MS, Fadul CE, Ornstein DL.
Systemic coagulation is activated in patients with meningioma and glioblastoma.
J Neurooncol. 2021 Oct 15
. doi: 10.1007/s11060-021-03865-w. PMID: 34652553. Observational study˰ ˍ