Current Neuro-Oncology

Volume 27 Number 8
20 March 2025

Home > Publications > Current Neuro-Oncology > Volume 27, Year 2025 > Number 8, 20 March

*Hu Y, Liu J, Tu J, Yang M, He Q, Li F, Xu X, Ji Z, Xu J, Zhong W, Yan M, Yang Y, Zhang H.
Rapid and Effective Neuronal Conversion of Human Glioblastoma In Vitro and In Vivo Using Potent Small Molecules.
Cell Prolif. 2025 Mar 11:e70013. doi: 10.1111/cpr.70013. PMID: 40070092. Laboratory investigation. ˍ

*Woo PYM, Pu JKS, Li LF, Wong DKK, Hui VKH, Chan DTM, Lee MWY, Chan TKT, Ho JMK, Cheung KM, Tse TPK, Lau SSN, Chow JSW, Ko NMW, Loong HHF, El-Helali A, Lam TC, Cheung FC, Poon WS.
Impact of alternating electric fields therapy for newly diagnosed WHO grade 4 astrocytoma on patient survival: a real-world propensity-score adjusted prospective multicenter study.
J Neurooncol. 2025 Mar 11. doi: 10.1007/s11060-025-04985-3. PMID: 40067514. Observational study. ˍ

Gust J, Cole BL, Ronsley R, Wilson AL, Seidel K, Wendler J, Pattabhi S, Brown C, Rawlings-Rhea SD, Shtanukhina N, Browd SR, Hauptman JS, Lee A, Ojemann JG, Crotty EE, Leary SES, Perez FA, Wright JN, Albert CM, Pinto N, Gardner RA, Vitanza NA, Jensen MC, Park JR.
Locoregional Infusion of EGFR806-CAR T Cells for Recurrent or Refractory Pediatric CNS Tumors: Results of the Completed BrainChild02 Phase 1 Clinical Trial.
Neuro Oncol. 2025 Mar 12:noaf064. doi: 10.1093/neuonc/noaf064. PMID: 40070357. Interventional study˰ ˍ

Mateos MK, Ajuyah P, Fuentes-Bolanos N, El-Kamand S, Barahona P, Altekoester AK, Mayoh C, Holliday H, Liu J, Cui L, Pfaff E, Mackay A, Resnick AC, Pinese M, Lau LMS, Khuong-Quang DA, Dias K, Goudie C, Salkeld A, Rokita JL, Jones DTW, Juretic N, Hayden E, Pfister SM, Kramm CM, Blattner-Johnson M, Jabado N, Tsoli M, Vittorio O, Mueller S, Guo Y, Tucker K, Waszak SM, Perreault S, Jones C, Wong-Erasmus M, Cowley MJ, Ziegler DS.
Germline analysis of an international cohort of pediatric diffuse midline glioma patients.
Neuro Oncol. 2025 Mar 12:noaf061. doi: 10.1093/neuonc/noaf061. PMID: 40072012. Translational study. ˍ

Ehinger E, Darabi A, Visse E, Edvardsson C, Tomasevic G, Cederberg D, Kinhult S, Rydelius A, Nilsson C, Belting M, Bengzon J, Siesjö P.
Antisecretory factor as add-on treatment for newly diagnosed glioblastoma, IDH wildtype: study protocol for a randomized double-blind placebo-controlled trial.
Trials. 2025 Mar 13;26(1):86. doi: 10.1186/s13063-025-08792-z. PMID: 40083039. Interventional study protocol. ˍ

Ian MA, Hannah SJ, Monish M.
Diagnostic accuracy of MRI without gadolinium for follow-up of pilocytic astrocytoma in the paediatric population.
J Clin Neurosci. 2025 Mar 13;135:111173. doi: 10.1016/j.jocn.2025.111173? PMID: 40086097. Observational study˰ ˍ

Karp JM, Kruser TJ.
Contouring with FLAIR: Targeting Peritumoral Edema (and Beyond) in Glioblastoma.
Int J Radiat Oncol Biol Phys. 2025 Mar 13;121(5):1182-1184. doi: 10.1016/j.ijrobp.2024.11.073. PMID: 40089338. Editorial˰ ˍ

Mayr L, Neyazi S, Schwark K, Trissal M, Beck A, Labelle J, Eder SK, Weiler-Wichtl L, Marques JG, de Biagi-Junior CAO, Lo Cascio C, Chapman O, Sridhar S, Kenkre R, Dutta A, Wang S, Wang J, Hack O, Nascimento A, Nguyen CM, Castellani S, Rozowsky JS, Groves A, Panditharatna E, Cruzeiro GAV, Haase RD, Tabatabai K, Madlener S, Wadden J, Adam T, Kong S, Miclea M, Patel T, Bruckner K, Senfter D, Lämmerer A, Supko J, Guntner AS, Palova H, Neradil J, Stepien N, Lötsch-Gojo D, Berger W, Leiss U, Rosenmayr V, Dorfer C, Dieckmann K, Peyrl A, Azizi AA, Baumgartner A, Slaby O, Pokorna P, Clark LM, Cameron A, Nguyen QD, Wakimoto H, Dubois F, Greenwald NF, Bandopadhayay P, Beroukhim R, Ligon K, Kramm C, Bronsema A, Bailey S, Stucklin AG, Mueller S, Skrypek M, Martinez N, Bowers DC, Jones DTW, Jones C, Jäger N, Sterba J, Müllauer L, Haberler C, Kumar-Sinha C, Chinnaiyan A, Mody R, Chavez L, Furtner J, Koschmann C, Gojo J, Filbin MG.
Effective targeting of PDGFRA-altered high-grade glioma with avapritinib.
Cancer Cell. 2025 Mar 13:S1535-6108(25)00070-4. doi: 10.1016/j.ccell.2025.02.018. PMID: 40086436. Translational study. ˍ

Carman-Esparza CM, Stine CA, Atay N, Kingsmore KM, Wang M, Woodall RT, Rockne RC, Cunningham JJ, Munson JM.
Interstitial fluid transport dynamics predict glioblastoma invasion and progression.
bioRxiv [Preprint]. 2025 Mar 14:2025.03.12.642840. doi: 10.1101/2025.03.12.642840. PMID: 40161666; PMCID: PMC11952461.

*Horikoshi K, Iimura Y, Suzuki H, Suzuki M, Sugano H, Kondo A.
Spontaneous regression of epileptogenic pilocytic astrocytoma with FGFR1-TACC1 fusion.
Childs Nerv Syst. 2025 Mar 14;41(1):129. doi: 10.1007/s00381-025-06789-2. PMID: 40085227. Case report. ˍ

Cao C, Wang L, Jiang F, Jin Q, Jin T, Huang S, Hu Q, Chen Y, Piao Y, Hua Y, Feng X, Zhou Y, Chen X.
Granulocyte-macrophage colony-stimulating factor for newly diagnosed glioblastoma.
Neoplasia. 2025 Mar 15;63:101156. doi: 10.1016/j.neo.2025.101156. PMID: 40090128. Interventional study. ˍ

Schönthal AH, Swenson S, Senecal FM, Mittenzwei R, Go JL, Chen TC.
Patient with recurrent grade 4 astrocytoma responding favorably to intranasal delivery of NEO100, highly pure perillyl alcohol: illustrative case.
J Neurosurg Case Lessons. 2025 Mar 17;9(11):CASE24683. doi: 10.3171/CASE24683. PMID: 40096739. Case report. ˍ

Neimantaite A, Carstam L, Gómez Vecchio T, Häggström I, Dunås T, Latini F, Zetterling M, Blomstrand M, Bartek J, Jensdottir M, Thurin E, Smits A, Jakola AS.
Survival prediction with radiomics for patients with IDH mutated lower-grade glioma.
J Neurooncol. 2025 Mar 18. doi: 10.1007/s11060-025-05006-z. PMID: 40100522. Observational study. ˍ

Wong ET, Cielo D, Svokos K, Doberstein C, Sampath P, Donahue JE, Punsoni M, Rodrigues N, Rothell F, Edwards R, Wang E, Riccelli T, Chuck C, Shaaya EA, Sastry R, Ali R, Shao B, Abdulrazeq H, Sun FW, Feler J, Santos Fontánez SE, Nieves NA, Dobertsein C, Dailey J, Yu C, Sarangi S, Elinzano H, Boxerman JL, Yu E, Safran H, Seyhan AA, El-Deiry WS, Keith S, Gokaslan ZL, Chen CC, Malik A.
IGV-001 cellular immunotherapy for newly diagnosed glioblastoma: overcoming the logistic challenge.
Front Oncol. 2025 Mar 18;15:1556450. doi: 10.3389/fonc.2025.1556450. PMID: 40171253. Interventional study protocol. ˍ

Yan M, Wang B, Han B, Li Z, Liu X, Liu P.
Insights From H3-Wildtype Diffuse Midline Glioma With EZHIP Overexpression.
Am J Surg Pathol. 2025 Mar 18. doi: 10.1097/PAS.0000000000002388. PMID: 40098385. Letter˰ ˍ

Foltyn-Dumitru M, Banan R, Schell M, Mahmutoglu MA, Kessler T, Wick W, Brugnara G, Bendszus M, Sahm F, Vollmuth P.
Histopathological and molecular characteristics of IDH-wildtype glioblastoma without contrast enhancement: implications for clinical outcomes.
Neuro Oncol. 2025 Mar 20:noaf070. doi: 10.1093/neuonc/noaf070. PMID: 40108725. Observational study˰ ˍ